MitoScore

MitoScore helps to select the embryos with higher potential for implantation increasing pregnancy rates for PGS

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MitoScore

MitoScore improves the chances of reproductive success

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Mitochondria are structures within cells that play an essential role in energy production.

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Mitochondria have their own DNA, that is known as mitochondrial DNA or mtDNA.

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mtDNA content in an embryo predicts its implantation potential.

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An increase in the mtDNA in the embryo indicates a low level of energy and implantation potential.

Advanced Reproductive Genetic Services

Overview

  • Mitoscore allows the selection of those embryos with the greatest probabilities of implantation.
  • It increases the possibilities of a viable pregnancy through IVF/PGS.
  • MitoScore allows us to select those embryos with the greatest probabilities for implantation, and more likely to generate a pregnancy through IVF/ PGS.
  • The clinical application of this work is the integration of MitoScore to the routine genetic analysis performed in a PGS analysis, in an IVF cycle.

Mitochondrial DNA content as a viability score in human euploid embryos: less is better. Diez-Juan et al.Fertil Steril. 2015 Jun11.doi:10.1016/j.fertnstert.2015.05.022

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Who should use MitoScore?

  • MitoScore helps IVF clinics to select the euploid embryos with higher implantation potential increasing the pregnancy rates of their patients.
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Advantages

  • Increased implantation and pregnancy rates in IVF.
  • Reduction of the number of multiple gestations.
  • It works using the same sample used for PGS, and doesn't require any additional work in the embryology laboratory.
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How it works

  • It is performed in an IVF cycle.
  • It is an additional step in the PGS process.
  • It works using the same sample used for PGS.
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